User quide
The RepDose online database offers the opportunity to search for subacute to chronic toxicity data of existing chemicals. It is linked to Ambit, a tool for structure search.
Terminology in RepDose	NOEL no observed effect level LOEL lowest LOEL in the study LOEL effect lowest observed effect level for this effect
Login	You have to register yourself as a RepDose member to access the RepDose database. This can be done by using the registration form on the start site (New Member). Select search options: There are two options for use of the RepDose internet query form: Analysis of toxicological data: For this purpose the user has to select the project "RepDose" on the Login form. Presection of chemicals by structure search using Ambit: For this purpose the user has to select the project "Ambit" on the LogIn form. Once the requested structures are found, the chemicals can be forwarded to the RepDose query form in order to search for their toxicological profile.
Query form	The query form consists of four parameter group: Chemical parameter Physical parameter Study parameter Target/effect parameter All parameters can be combined in any order. The programme demands to refine search parameters if more than 100 entries are found. On the right side four buttons are arranged: starts a new structure search in the entire database starts a new tox-search in the entire database resets search parameters activate to run the query after search parameters have been changed
Result table	Once the query is done a result table is shown below the parameter template. The user is allowed to modify the result table by himself by using the show options. It is possible to download the results as a PDF file.